How AI is recalibrating the UK’s geography of innovation 

The UK’s AI future depends on empowering innovation beyond London’s Golden Triangle.

By Karim Bahou | edited by Patricia Cullen | Sep 11, 2026
Sister
Karim Bahou, Head of Innovation, Sister

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The UK has the potential to be the number one destination for AI globally. We rank third in the world for AI talent and are Europe’s leading AI hub, powered by a thriving start-up community which raised £2.8bn in venture capital in the first half of 2026

When it comes to innovation, our strength as a nation lies in our entrepreneurs and early-stage businesses. Whether it’s robotics in Birmingham, applied AI in Manchester, or life sciences and data analytics in Edinburgh, the UK is a rich tapestry of AI specialisms, driven by start-ups and supported by growing innovation clusters. 

The North West has seen a 2.41 fold increase in the number of active AI companies since 2019 – outpacing London’s growth rate of 2.13. Manchester has been voted the UK’s “most AI-ready” city in the SAS AI Cities Index three years running. Scotland hosts the highest concentration of AI life sciences companies outside of the Golden Triangle of London, Cambridge and Oxford, supported by a network of dedicated research and innovation hubs across the country. 

If we are to compete in the global arena, investors and government need to lean into the strengths of our growing regions and innovation corridors across the UK. As the Burnham administration sets the direction for the UK’s AI strategy with the new AI Taskforce, this presents an opportunity to redraw our innovation map and support the regional start-ups driving real growth. 

Decentralising innovation 
The UK’s focus on the south as the home of innovation is an outdated narrative that’s holding us back from reaching our full potential. Nearly 80% of all UK venture capital funding is sat in the Golden Triangle. This creates an imbalance where intellectual property and breakthroughs born in regional labs are forced to migrate to this small cluster for the resources they need to scale. 

This overlooks the huge potential we have in our regions, with non-capital cities like Bristol, Edinburgh and Manchester fast outpacing the south for innovative growth. Recent research by Beauhurst shows that these cities have grown by more than 30% in innovation employment since 2019. By contrast, London has only grown 1% as a whole in the same amount of time. 

Our regional clusters have all the same ingredients as the Golden Triangle for start-up and innovation success, with world class universities, multinational tech companies and commercial opportunities. Redistributing opportunities and leveraging our regional strengths is how we’ll sustainably fuel our innovation economy. 

Empowering our AI champions
Changing the innovation narrative is important to understanding where the real AI opportunities are across the UK, but this needs to be paired with dedicated investment and ecosystem support. 

We’re not only seeing growth in AI in software and SaaS applications, but also expansions into health and biotech and breakthroughs in industrial AI across construction, energy and manufacturing. The North East in particular is set to become an AI powerhouse, with the government-backed AI Growth Zone expected to generate 5,000 new jobs and £30bn in investment for the region. Despite this vote of confidence, there continues to be a funding disparity with 68% of funded AI start-ups coming from London

Major regional investments like the North East AI Growth Zone and incubators like Yorkshire AI Labs are critical to helping early-stage start-ups access the funding they need. However, for start-ups to successfully scale they need to be part of a wider ecosystem that helps them overcome challenges unique to AI businesses, like computational costs, talent competition and regulatory hurdles. 

The University of Manchester’s Unit M Deep Tech Accelerator, for example, helps researchers and founders turn their AI and science innovations into commercial businesses. Active talent networks like Turing Innovation Catalyst Manchester help connect AI leaders from across the North of England to collaborate and share ideas. 

Regional hubs have an important role to play in progressing this shift, providing early-stage AI businesses with the tools they need to grow beyond capital, such as specialised talent, infrastructure and peer-to-peer support.

Capitalising on our regional strengths
It’s not just our regional specialisms that offer huge opportunities for AI growth. Across the UK, our regional cities offer entrepreneurs a more affordable cost of living, rich culture and community, and the physical space they need to grow an idea into a successful business.  

Cities such as Manchester have 30% lower operational costs compared to places like London, offer a better chance for employees to get on the property ladder, and have high graduate retention rate, with over 50% of students from outside Manchester choosing to stay after university. These factors can help create a more stable start-up environment for entrepreneurs, enabling them to focus on their primary priority: scaling their innovations. 

Innovation districts like Sister act as key connectors, pairing high-growth businesses with affordable workspaces, and access to a network of industry-leading experts, cutting-edge research and highly-skilled talent pools. Equipping AI entrepreneurs with these essential resources provides the strong foundation they need to build, scale, and achieve long-term success. 

The new innovation geography 
As the UK strives to become a leader in AI, we should use this opportunity to recalibrate our innovation map and champion the AI start-ups from across the country. Early stage businesses are proving that AI success does not just live in London – our regions are thriving in specific sectors and growing rapidly.

If we want to establish the UK as an AI powerhouse, we need to recognise this regional potential and tap into the opportunities by encouraging devolution, distributed investment, and support for the innovation ecosystems that are helping these businesses grow.

The UK has the potential to be the number one destination for AI globally. We rank third in the world for AI talent and are Europe’s leading AI hub, powered by a thriving start-up community which raised £2.8bn in venture capital in the first half of 2026

When it comes to innovation, our strength as a nation lies in our entrepreneurs and early-stage businesses. Whether it’s robotics in Birmingham, applied AI in Manchester, or life sciences and data analytics in Edinburgh, the UK is a rich tapestry of AI specialisms, driven by start-ups and supported by growing innovation clusters. 

The North West has seen a 2.41 fold increase in the number of active AI companies since 2019 – outpacing London’s growth rate of 2.13. Manchester has been voted the UK’s “most AI-ready” city in the SAS AI Cities Index three years running. Scotland hosts the highest concentration of AI life sciences companies outside of the Golden Triangle of London, Cambridge and Oxford, supported by a network of dedicated research and innovation hubs across the country. 

Karim Bahou Head of Innovation, Sister

Dr Karim Bahou, Head of Innovation at Sister - Manchester’s £1.7bn innovation district - about... Read more

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